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理学院2018-2019学年秋季第三周学术报告(4)

发布时间:2018-09-19

学 术 报 告

 

报告题目:Can material stiffness influence bacterial adhesion? From both bulk material and surface properties

 

报告学者:Ren Qun博士

 

报告者单位Empa - Swiss Federal Laboratories for Materials Science and Technology 

 

报告时间2018年9月20日(星期四)下午4:00—5:00

 

 

报告地点生命与科学与生物工程研究院二楼会议室

 

摘要:Among nosocomial infection, infections associated to materials are the most frequent and severe due to biofilm formation. As a heterogeneous community embedded into a matrix of polymers, bacteria in biofilms are highly resistant to environmental stress, antibiotic and host immune response. To avoid biofilm formation, prevention of bacterial adhesion, the first step of biofilm development, should mitigate the infection problem. We are particular interested in biophysical approaches to prevent bacterial contamination by modulating material mechanical properties and surface topographies. To do so, it is essential to understand the underlying mechanisms of bacteria and surface interactions. Bacterial adhesion to surfaces is a complex process that is driven both by the physicochemical properties of the material and bacterial surfaces and the mechanosensing abilities of bacteria. In this talk I will provide new mechanistic insight into the impact of material biophysical properties on the initial bacterial adhesion. I will illustrate our findings with biomedically relevant examples such as pathogen adhesion on stainless steel surfaces having different roughness and polydimethylsiloxane (PDMS) having different viscoelasticity.

 

报告人简介: Qun Ren is a senior scientist leading a research group with research focus on designing new approaches to battle against bacterial infectious disease and to detect antimicrobial resistance. One of the primary research themes in Dr. Ren’s group is to understand the basic mechanisms of bacterial adhesion on material surfaces, with the ultimate goal to reduce and prevent bacterial pathogen infections in the clinical settings.

 

主办教师:吴松梅

欢迎广大同学老师积极踊跃参加!